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GSK2879552 dihydrochloride - LSD1 Inhibitor. CAS# 1902123-72-1 60306 and decrease markers of DNA

GSK2879552 dihydrochloride - LSD1 Inhibitor. CAS# 1902123-72-1 60306 and decrease markers of DNA

Name: GSK2879552 dihydrochloride - LSD1 Inhibitor. CAS# 1902123-72-1 60306 and decrease markers of DNA
Brand: buddy-carsharing.at
SKU: 90129285943
Price: 50.00 USD
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SKU: 90129285943

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GSK2879552 dihydrochloride - LSD1 Inhibitor. CAS# 1902123-72-1 60306 and decrease markers of DNAGSK2879552 dihydrochloride, CAS No. 1902123 72 1, is a highly potent, selective and orally bioavailable irreversible inhibitor of Lysine Specific Demethylase 1 (LSD1). It is highly selective over related enzymes such as MAO A B. A proliferation screen of cell lines representing a number of tumor types indicated that small cell lung carcinoma (SCLC) is sensitive to GSK2879552s inhibition. It increases H3K4 methylation selectively at genomic regions

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Description

and decrease markers of DNA damage in these cells

JNJ-42041935 was dosed to mice orally at 100 µM/kg once per day

Molecular Weight: 344

12(8):1442-52

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