AZ5104 - CAS# 1421373-98-9 308 EC50 = 280 nmol/L)

EC50 = 280 nmol/L)

5-diyl)dibenzimidamide dihydrochloride

InChiKey: TXZPMHLMPKIUGK-UHFFFAOYSA-N

20 min before testing) decreased the number of cocaine responses in a dose-dependent manner during the first 15-min cocaine-free interval

AZ5104 - CAS# 1421373-98-9 308 EC50 = 280 nmol/L)AZ5104, CAS No. 1421373 98 9, is a demethylated metabolite of AZD 9291. AZ 5104 was identified to exhibit 5 fold potency compared to AZD 9291, which is currently in clinical trial. AZ5104 is a potent EGFR inhibitor with IC50 of <1 nM, 6 nM, 1 nM, and 25 nM for EGFR (L858R T790M), EGFR (L858R), EGFR (L861Q), and EGFR (wildtype), respectively. Product information CAS Number: 1421373 98 9 Molecular Weight: 485. 58 Formula: C27H31N7O2 Synonym: AZ5104 AZ