Lenvatinib - CAS# 417716-92-8 K474 PubMed Central PMCID: PMC4707128
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Lenvatinib - CAS# 417716-92-8 K474 PubMed Central PMCID: PMC4707128Lenvatinib, also known as E7080, is a synthetic, orally available inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR FLK 1) tyrosine kinase with potential antineoplastic activity. E7080 blocks VEGFR2 activation by VEGF, resulting in inhibition of the VEGF receptor signal transduction pathway, decreased vascular endothelial cell migration and proliferation, and vascular endothelial cell apoptosis. Product information
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