Takinib - CAS# 1111556-37-6 60071 22)11-7-5-10(6-8-11)18-14-9-15(19)12-3-1-2-4-13(12)16(14)20/h1-9

22)11-7-5-10(6-8-11)18-14-9-15(19)12-3-1-2-4-13(12)16(14)20/h1-9

A small molecule inhibitor of the Wnt antagonist secreted frizzled-related protein-1 stimulates bone formation

InChi: InChI=1S/C24H27N5O2/c1-2-31-23(30)10-14-26-21-17-22(28-24(27-21)20-9-5-6-13-25-20)29-15-11-18-7-3-4-8-19(18)12-16-29/h3-9

1-b]quinazoline-4-carboxamide

Takinib - CAS# 1111556-37-6 60071 22)11-7-5-10(6-8-11)18-14-9-15(19)12-3-1-2-4-13(12)16(14)20/h1-9Takinib, CAS No. 1111556 37 6, is a selective TAK1 inhibitor that induces apoptosis following TNF stimulation in cell models of rheumatoid arthritis and metastatic breast cancer. Takinib is an inhibitor of autophosphorylated and non phosphorylated TAK1 that binds within the ATP binding pocket and inhibits by slowing down the rate limiting step of TAK1 activation. Product information CAS Number: 1111556 37 6 Molecular Weight: 322. 36 Formula: