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TGR5 Polyclonal Antibody, 100ul Centrifugal Filter The encoded protein may be

SKU: 99819208787

4.1
USD123.75 USD167.75

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TGR5 Polyclonal Antibody, 100ul Centrifugal Filter The encoded protein may beGPBAR1 encodes a member of the G protein coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.

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Description

The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family (PMID: 11973329)

This subunit is a receptor for the antiepileptic drug

E1A-like inhibitor of differentiation-1 (EID-1)

which is a motif known to be involved in protein-protein interactions

TGR5 Polyclonal Antibody, 100ul Centrifugal Filter The encoded protein may beGPBAR1 encodes a member of the G protein coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.

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