DOC11 Polyclonal Antibody, 50ul Cryogenic Vials Vora (1981) [PubMed 6451249] determined

Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4

The protein encoded by BAG4 is a member of the BAG1-related protein family

Four transcript variants encoding different isoforms have been found for this gene

Differential expression of this gene may be associated with progression of breast and prostate cancer

DOC11 Polyclonal Antibody, 50ul Cryogenic Vials Vora (1981) [PubMed 6451249] determinedThe DHR 2 domain is necessary for the GEF activity.,Guanine nucleotide exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.,miscellaneous:'Zizim' means 'spike' in Hebrew.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the DOCK family.,Contains 1 DHR 1 (CZH 1) domain.,Contains 1 DHR 2 (CZH 2) domain.,Contains 1 PH domain.,subunit: Interacts with CDC42.,