EGFR(Phospho Tyr1197) Polyclonal Antibody, 20ul Bottles Alternate splicing results in multiple

Alternate splicing results in multiple transcript variants of this gene

TNK2 encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs

and is involved in the process of phagocytosis and clearing of immune complexes

which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM)

EGFR(Phospho Tyr1197) Polyclonal Antibody, 20ul Bottles Alternate splicing results in multipleThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.