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Sgo1(Phospho Ser14) Polyclonal Antibody, 20ul Lentiviral Packaging Among its related pathways are

SKU: 96573448995

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Sgo1(Phospho Ser14) Polyclonal Antibody, 20ul Lentiviral Packaging Among its related pathways areThe protein encoded by this gene is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found

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Description

Among its related pathways are Transport to the Golgi and subsequent modification and Chaperonin-mediated protein folding

in contrast to the other GAP1 family members

Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis

and thus may be involved in the regulation of alternative splicing

Sgo1(Phospho Ser14) Polyclonal Antibody, 20ul Lentiviral Packaging Among its related pathways areThe protein encoded by this gene is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found

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