p47-phox Polyclonal Antibody, 100ul[BT-AP06793] Endonucleases & Exonucleases Defects in CYB5A are a

Defects in CYB5A are a cause of type IV hereditary methemoglobinemia

Very large introns typically separate the exons encoding the VPS10 domain

Belongs to the resistin/FIZZ family

These chains associate via disulfide linkages to form the heterodimeric enzyme

p47-phox Polyclonal Antibody, 100ul[BT-AP06793] Endonucleases & Exonucleases Defects in CYB5A are aThe protein encoded by NCF1 (neutrophil cytosolic factor 1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in NCF1 have been associated with chronic granulomatous disease.