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IκB-alpha Polyclonal Antibody, 50ul[BT-AP10545] Gel & Buffers Mutations in this gene cause
IκB-alpha Polyclonal Antibody, 50ul[BT-AP10545] Gel & Buffers Mutations in this gene cause
IκB-alpha Polyclonal Antibody, 50ul[BT-AP10545] Gel & Buffers Mutations in this gene cause
IκB-alpha Polyclonal Antibody, 50ul[BT-AP10545] Gel & Buffers Mutations in this gene cause

IκB-alpha Polyclonal Antibody, 50ul[BT-AP10545] Gel & Buffers Mutations in this gene cause

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IκB-alpha Polyclonal Antibody, 50ul[BT-AP10545] Gel & Buffers Mutations in this gene causeThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4

synaptogenesis and lymphocyte activation

are located within a 1

The encoded protein can multimerize and may function as an ion channel

IκB-alpha Polyclonal Antibody, 50ul[BT-AP10545] Gel & Buffers Mutations in this gene causeThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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