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Rb(Phospho Ser612) Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) where it is transcriptionally regulated

SKU: 8403127047

4.6
USD123.75 USD164.75

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Rb(Phospho Ser612) Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) where it is transcriptionally regulatedThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

where it is transcriptionally regulated by AP-2epsilon and Ets-1

Defects in this gene are a cause of pyruvate dehydrogenase deficiency which results in neurological dysfunction and lactic acidosis in infancy and early childhood

Elongation of very long chain fatty acids protein 1 (ELOVL1)

5)-trisphosphate and inositol-1

Rb(Phospho Ser612) Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) where it is transcriptionally regulatedThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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