MAN1 Rabbit Polyclonal Antibody, 50ul Cell Screening and Imaging CKLF like MARVEL transmembrane domain

CKLF like MARVEL transmembrane domain containing 2 encoded by CMTM2 may play an important role in testicular development

Defects in this gene result in premature ovarian failure type 5

This hormone contracts smooth muscle during parturition and lactation

Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification

MAN1 Rabbit Polyclonal Antibody, 50ul Cell Screening and Imaging CKLF like MARVEL transmembrane domainThis locus encodes a LEM domain containing protein. The encoded protein functions to antagonize transforming growth factor beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis Buschke Ollendorff syndrome and melorheostosis.