Sgo1 Polyclonal Antibody, 50ul Custom DNA Oligos This gene encodes the cytosolic

This gene encodes the cytosolic isozyme

disease:A chromosomal rearrangement involving CTNNB1 may be a cause of salivary gland pleiomorphic adenomas (PA)

The functional domains of p53 family proteins include an N-terminal transactivation domain| a central DNA-binding domain and an oligomerization domain

and a transcriptional activation domain in their C-terminus

Sgo1 Polyclonal Antibody, 50ul Custom DNA Oligos This gene encodes the cytosolicShugoshin like 1 encoded by SGOL1 is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found