TGF beta RI(Phospho Ser165) Polyclonal Antibody, 50ul Cell Proliferation The SSH family appears to

The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo

The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced)

tissue specificity:Widely expressed with high levels in heart

The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1)

TGF beta RI(Phospho Ser165) Polyclonal Antibody, 50ul Cell Proliferation The SSH family appears toThe protein encoded by this gene forms a heteromeric complex with type II TGF beta receptors when bound to TGF beta, transducing the TGF beta signal from the cell surface to the cytoplasm. The encoded protein is a serine threonine protein kinase. Mutations in this gene have been associated with Loeys Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.