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SMAD7 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Transcripts of this gene have

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SMAD7 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Transcripts of this gene haveThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF beta receptor type 1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding

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Description

Transcripts of this gene have been reported in specimens of human testis

which is several orders of magnitude faster than conventional molecular motor proteins

Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3)

Mannose receptor C type 2 plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands

SMAD7 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Transcripts of this gene haveThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF beta receptor type 1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding

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