EGF Receptor(Phospho-Tyr1045) Rabbit Polyclonal Antibody, 100ul Bottle-Top Dispenser Growth arrest and DNA damage-inducible

Growth arrest and DNA damage-inducible protein GADD45 gamma encoded by GADD45G responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase

the full length nature of some of these variants has not been determined

Tyrosine phosphorylation seems to occur only at the plasma membrane

Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis

EGF Receptor(Phospho-Tyr1045) Rabbit Polyclonal Antibody, 100ul Bottle-Top Dispenser Growth arrest and DNA damage-inducibleThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.