PAK Alpha/Beta/Gamma Polyclonal Antibody, 20ul[BT-AP06897] Buffer Solutions PRKDC encodes the catalytic subunit

PRKDC encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK)

The protein encoded by MARCKS is a substrate for protein kinase C

Ser392 is dephosphorylated by PP2A

This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 17

PAK Alpha/Beta/Gamma Polyclonal Antibody, 20ul[BT-AP06897] Buffer Solutions PRKDC encodes the catalytic subunitPAK1 encodes a family member of serine threonine p21 activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.