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p47-phox Polyclonal Antibody, 100ul[BT-AP06795] Thermal Control all of which are guanine-nucleotide

SKU: 63635277482

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p47-phox Polyclonal Antibody, 100ul[BT-AP06795] Thermal Control all of which are guanine-nucleotideNeutrophil cytosolic factor 1 encoded by NCF1 is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in NCF1 have been associated with chronic granulomatous disease.

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Description

all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases

It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane

Alternatively spliced variants encoding different isoforms have been identified

The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3

p47-phox Polyclonal Antibody, 100ul[BT-AP06795] Thermal Control all of which are guanine-nucleotideNeutrophil cytosolic factor 1 encoded by NCF1 is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in NCF1 have been associated with chronic granulomatous disease.

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