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FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling &Storage PKC family members also serve

SKU: 61336067720

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FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling &Storage PKC family members also serveThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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Description

PKC family members also serve as major receptors for phorbol esters

|PTM:Monomethylation at Arg-4 by PRMT1 favors acetylation at Lys-9 and Lys-13

An important paralog of this gene is HSH2D

and has been shown to stimulate the production of several other cytokines

FAK(Phospho Tyr577) Polyclonal Antibody, 50ul Liquid Handling &Storage PKC family members also serveThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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