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CD56 Polyclonal Antibody, 50ul[BT-AP01906] Plasmid Preparation Inhibits basal activity of MAPK8/JNK

SKU: 60112437391

4.5
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CD56 Polyclonal Antibody, 50ul[BT-AP01906] Plasmid Preparation Inhibits basal activity of MAPK8/JNKCASP9 encodes a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Caspase 9 can undergo autoproteolytic processing and activation by the apoptosome, a

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Description

Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF)

The processed form is active and the unprocessed form acts as an inhibitor (I kappa B-like)| being able to form cytosolic complexes with NF-kappa B| trapping it in the cytoplasm

This gene is a member of the melanoma antigen gene (MAGE) family

May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology

CD56 Polyclonal Antibody, 50ul[BT-AP01906] Plasmid Preparation Inhibits basal activity of MAPK8/JNKCASP9 encodes a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Caspase 9 can undergo autoproteolytic processing and activation by the apoptosome, a

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