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VHL Polyclonal Antibody, 100ul[BT-AP15472] miRNA / siRNA Synthesis PLCH2 is a member of

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VHL Polyclonal Antibody, 100ul[BT-AP15472] miRNA / siRNA Synthesis PLCH2 is a member ofVon Hippel Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin 2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and

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Description

PLCH2 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave PtdIns(4

these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related

mutations in either gene may contribute to these disorders

making it an important component of the non-specific immune system

VHL Polyclonal Antibody, 100ul[BT-AP15472] miRNA / siRNA Synthesis PLCH2 is a member ofVon Hippel Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin 2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and

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