Egr-1 Monoclonal Antibody, 100ul Cell Dissociation such as detergents and solvents

such as detergents and solvents

Biochemical and genetic data suggest a role as a tumor suppressor

This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL)

and is used as a fluorescent tracer in trasfection and transgenic experiments

Egr-1 Monoclonal Antibody, 100ul Cell Dissociation such as detergents and solventsThe protein encoded by this gene belongs to the EGR family of C2H2 type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene.