Cortactin(Phospho Tyr421) Polyclonal Antibody, 20ul Centrifugal Filter The D4Z4 repeat is polymorphic
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Cortactin(Phospho Tyr421) Polyclonal Antibody, 20ul Centrifugal Filter The D4Z4 repeat is polymorphicThis gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase
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