RN123 Polyclonal Antibody, 50ul Antibody Development This endoplasmic reticulum protein is

This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids

May regulate osteoblast proliferation and differentiation

called PPARs

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules

RN123 Polyclonal Antibody, 50ul Antibody Development This endoplasmic reticulum protein isThe protein encoded by this gene contains a C terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein protein and protein DNA interactions, and an N terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin dependent kinase inhibitor 1B which is also known as p27 or KIP1. Alternative splicing results in multiple transcript variants.