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p53 Polyclonal Antibody, 100ul[BT-AP06833] Virus Packaging is due to mutations in

SKU: 3478439338

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p53 Polyclonal Antibody, 100ul[BT-AP06833] Virus Packaging is due to mutations inTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

is due to mutations in the ALMS1 gene

The protein encoded by this gene is 75% identical to the mouse homolog

thereby releasing the attached protein from the plasma membrane

This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily

p53 Polyclonal Antibody, 100ul[BT-AP06833] Virus Packaging is due to mutations inTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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