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Phospho-ATRIP (S224) Polyclonal Antibody, 50ul Long RNA Synthesis Members of this gene family

SKU: 34175880201

4.3
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Phospho-ATRIP (S224) Polyclonal Antibody, 50ul Long RNA Synthesis Members of this gene familyATRIP (ATR interacting protein) encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for ATRIP.

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Description

Members of this gene family typically contain a paired box domain

|PTM:O-glycosylated

which act as protein phospho-tyrosine binding domains

It is found among several proteins that bind directly to retinoblastoma protein

Phospho-ATRIP (S224) Polyclonal Antibody, 50ul Long RNA Synthesis Members of this gene familyATRIP (ATR interacting protein) encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for ATRIP.

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