PCSK9 Rabbit Polyclonal Antibody, 100ul[BT-AP11848] Hybridoma Antibody Sequencing SEPT5 is mapped to 22q11

SEPT5 is mapped to 22q11

The encoded protein (solute carrier family 25 member 12) localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane

Non-receptor tyrosine-protein kinase TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits

The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase

PCSK9 Rabbit Polyclonal Antibody, 100ul[BT-AP11848] Hybridoma Antibody Sequencing SEPT5 is mapped to 22q11Proprotein convertase subtilisin kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1. It is the 9th member of the proprotein convertase family of proteins that activate other proteins. Similar genes (orthologs) are found across many species. As with many proteins, PCSK9 is inactive when first synthesized, because a section of peptide chains blocks their activity; proprotein convertases remove that section to activate