Tuberin/TSC2(Phospho-Ser664) Rabbit Polyclonal Antibody, 50ul Long RNA Synthesis The second transcript (1b) retains

The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin

Following type I IFN binding to cell surface receptors| Jak kinases (TYK2 and JAK1) are activated| leading to tyrosine phosphorylation of STAT1 and STAT2

Found in a mRNA splicing-dependent exon junction complex (EJC) with DEK

UBE4B encodes an additional conjugation factor

Tuberin/TSC2(Phospho-Ser664) Rabbit Polyclonal Antibody, 50ul Long RNA Synthesis The second transcript (1b) retainsMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.