c-Fms(Phospho Tyr561) Polyclonal Antibody, 50ul Molecular Biology Chromosomal translocations involving this gene

Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia

PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes

Two alternately spliced transcripts encoding two protein isoforms have been identified

the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS

c-Fms(Phospho Tyr561) Polyclonal Antibody, 50ul Molecular Biology Chromosomal translocations involving this geneThe protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1 PDGF