EI24 Rabbit Polyclonal Antibody, 20ul Vacuum Aspirator Two alternatively spliced transcript variants

Two alternatively spliced transcript variants that encode different proteins have been described for this gene

Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma

2-cyclic phosphate to form inositol 1-phosphate

and MAPK11/p38-beta

EI24 Rabbit Polyclonal Antibody, 20ul Vacuum Aspirator Two alternatively spliced transcript variantsThis gene encodes a putative tumor suppressor and has higher expression in p53 expressing cells than in control cells and is an immediate early induction target of p53 mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24 a region frequently altered in cancers. Alternative splicing results in multiple transcript