Tau Polyclonal Antibody, 20ul[BT-AP08842] Transporters Heterogeneous nuclear RNAs (hnRNAs) which

Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes

Two transcript variants encoding the same protein have been identified

The encoded protein directly interacts with another large centrosomal protein and is required to anchor microtubules at the centrosome

The first three are located together on chromosome 2

Tau Polyclonal Antibody, 20ul[BT-AP08842] Transporters Heterogeneous nuclear RNAs (hnRNAs) whichMAPT encodes the microtubule associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico