ANXA8 Rabbit Polyclonal Antibody, 20ul Plasmid Preparation Acyl-protein thioesterase 1 functions as

Acyl-protein thioesterase 1 functions as a homodimer

|subunit:When phosphorylated| interacts directly with the PIK3R1 subunit of phosphoinositide 3-kinase and the SH2 domains of GRB2| GRAP| GRAP2| PLCG1 and PLCG2

while it has no activity on monomethylated residues

The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 light chain

ANXA8 Rabbit Polyclonal Antibody, 20ul Plasmid Preparation Acyl-protein thioesterase 1 functions asThis gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.