MBP Monoclonal Antibody, 100ul Cryogenic Vials The Transcription factor 4 recognizes

The Transcription factor 4 recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers

Expression of this gene has been found to be upregulated in small cell lung cancers

which suggests its involvement in a regulated signaling process

tissue specificity:Monocytic/myeloid lineage cells

MBP Monoclonal Antibody, 100ul Cryogenic Vials The Transcription factor 4 recognizesThis gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified.