PLC gamma1(Phospho-Ser1248) Rabbit Polyclonal Antibody, 50ul Pipette Controller Deletion of this gene or

Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies

This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules

Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation

NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines| oxidant-free radicals| ultraviolet irradiation| and bacterial or viral products

PLC gamma1(Phospho-Ser1248) Rabbit Polyclonal Antibody, 50ul Pipette Controller Deletion of this gene orThe protein encoded by this gene catalyzes the formation of inositol 1 4 5 trisphosphate and diacylglycerol from phosphatidylinositol 4 5 bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor mediated tyrosine kinase activators. For example when activated by SRC the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi where it