DNA Ligase I Polyclonal Antibody, 20ul Reservoirs Members of the aquaporin family

Members of the aquaporin family are multiple pass transmembrane proteins that form homotetramers to facilitate the flow of water across the plasma membrane

but the exact function of the encoded protein is unknown

thereby affecting various biological functions

GO annotations related to this gene include protein kinase binding

DNA Ligase I Polyclonal Antibody, 20ul Reservoirs Members of the aquaporin familyLIG1 encodes a member of the ATP dependent DNA ligase protein family. DNA ligase 1 functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA damaging agents. Disruption of LIG1 may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.