IMP cyclohydrolase Monoclonal Antibody, 50ul Lentiviral Packaging The gene is a member

The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family

Mutations in this gene are associated with achondrogenesis

including Brugada syndrome and short QT syndrome

Multiple transcript variants encoding at least two different isoforms have been described for this gene

IMP cyclohydrolase Monoclonal Antibody, 50ul Lentiviral Packaging The gene is a memberThis gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA ribosiduria.